Cargando…

IRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress

Physiological and pathophysiological stress attenuates global translation via phosphorylation of eIF2α. This in turn leads to the reprogramming of gene expression that is required for adaptive stress response. One class of cellular messenger RNAs whose translation was reported to be insensitive to e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thakor, Nehal, Holcik, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258125/ https://www.ncbi.nlm.nih.gov/pubmed/21917851 http://dx.doi.org/10.1093/nar/gkr701

Ejemplares similares

An internal ribosomal entry site mediates redox-sensitive translation of Nrf2
por: Li, Wenge, et al.
Publicado: (2010)

40S recruitment in the absence of eIF4G/4A by EMCV IRES refines the model for translation initiation on the archetype of Type II IRESs
por: Chamond, Nathalie, et al.
Publicado: (2014)

eIF2β is critical for eIF5-mediated GDP-dissociation inhibitor activity and translational control
por: Jennings, Martin D., et al.
Publicado: (2016)

An interaction between eIF4A3 and eIF3g drives the internal initiation of translation
por: Chang, Jeeyoon, et al.
Publicado: (2023)

Mechanisms of translational regulation by a human eIF5-mimic protein
por: Singh, Chingakham Ranjit, et al.
Publicado: (2011)

PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1
por: Gao, Guozhen, et al.
Publicado: (2017)

Gcn2 eIF2α kinase mediates combinatorial translational regulation through nucleotide motifs and uORFs in target mRNAs
por: Chikashige, Yuji, et al.
Publicado: (2020)

Distinct 5′ UTRs regulate XIAP expression under normal growth conditions and during cellular stress
por: Riley, Alura, et al.
Publicado: (2010)

Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5
por: Loughran, Gary, et al.
Publicado: (2012)

Differential regulation of CHOP translation by phosphorylated eIF4E under stress conditions
por: Chen, Yi-Jiun, et al.
Publicado: (2010)

eIF3j inhibits translation of a subset of circular RNAs in eukaryotic cells
por: Song, Zhenxing, et al.
Publicado: (2022)

Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation
por: Kozel, Caitlin, et al.
Publicado: (2016)

PERK/eIF2α signaling inhibits HIF-induced gene expression during the unfolded protein response via YB1-dependent regulation of HIF1α translation
por: Ivanova, Iglika G, et al.
Publicado: (2018)

Large-scale movement of eIF3 domains during translation initiation modulate start codon selection
por: Llácer, Jose L, et al.
Publicado: (2021)

Eukaryotic initiation factor (eIF) 3 mediates Barley Yellow Dwarf Viral mRNA 3′–5′ UTR interactions and 40S ribosomal subunit binding to facilitate cap-independent translation
por: Bhardwaj, Usha, et al.
Publicado: (2019)

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
por: B’chir, Wafa, et al.
Publicado: (2013)

Translation reprogramming by eIF3 linked to glioblastoma resistance
por: Bertorello, Juliette, et al.
Publicado: (2020)

Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins
por: Cridge, Andrew G., et al.
Publicado: (2010)

Eukaryotic translation initiation factor eIF5 promotes the accuracy of start codon recognition by regulating P(i) release and conformational transitions of the preinitiation complex
por: Saini, Adesh K., et al.
Publicado: (2014)

RNA helicase-dependent gene looping impacts messenger RNA processing
por: Terrone, Sophie, et al.
Publicado: (2022)

The activity of the HIV-1 IRES is stimulated by oxidative stress and controlled by a negative regulatory element
por: Gendron, Karine, et al.
Publicado: (2011)

Genomic targets of the IRE1-XBP1s pathway in mediating metabolic adaptation in epithelial plasticity
por: Qiao, Dianhua, et al.
Publicado: (2023)

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling
por: Roy, Rajat, et al.
Publicado: (2014)

The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner
por: Jayaraman, Swaathi, et al.
Publicado: (2017)

Epigenetic regulation by RARα maintains ligand-independent transcriptional activity
por: Laursen, Kristian B., et al.
Publicado: (2012)

Effects of cooperation between translating ribosome and RNA polymerase on termination efficiency of the Rho-independent terminator
por: Li, Rui, et al.
Publicado: (2016)

The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus
por: Anderson, Brent W, et al.
Publicado: (2021)

The eIF3 complex of Leishmania—subunit composition and mode of recruitment to different cap-binding complexes
por: Meleppattu, Shimi, et al.
Publicado: (2015)

Essential role of eIF5-mimic protein in animal development is linked to control of ATF4 expression
por: Hiraishi, Hiroyuki, et al.
Publicado: (2014)

Distinct CoREST complexes act in a cell-type-specific manner
por: Mačinković, Igor, et al.
Publicado: (2019)

HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIα
por: Štros, Michal, et al.
Publicado: (2009)

Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity
por: Wang, Jing, et al.
Publicado: (2017)

Regulatory modules function in a non-autonomous manner to control transcription of the mbp gene
por: Dib, Samar, et al.
Publicado: (2011)

Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5′ leader regions
por: Steinberger, Jutta, et al.
Publicado: (2020)

SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner
por: Sutinen, Päivi, et al.
Publicado: (2014)

Shwachman–Bodian–Diamond syndrome (SBDS) protein deficiency impairs translation re-initiation from C/EBPα and C/EBPβ mRNAs
por: In, Kyungmin, et al.
Publicado: (2016)

A novel cis-acting element from the 3′UTR of DNA damage-binding protein 2 mRNA links transcriptional and post-transcriptional regulation of gene expression
por: Melanson, Brian D., et al.
Publicado: (2013)

Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A
por: Kelly, Richard D. W., et al.
Publicado: (2012)

HDAC1 negatively regulates selective mitotic chromatin binding of the Notch effector RBPJ in a KDM5A-dependent manner
por: Dreval, Kostiantyn, et al.
Publicado: (2019)

YdiV regulates Escherichia coli ferric uptake by manipulating the DNA-binding ability of Fur in a SlyD-dependent manner
por: Zhang, Fengyu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_psv501clf9uprdqogk0c6bf04c