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IRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress
Physiological and pathophysiological stress attenuates global translation via phosphorylation of eIF2α. This in turn leads to the reprogramming of gene expression that is required for adaptive stress response. One class of cellular messenger RNAs whose translation was reported to be insensitive to e...
Autores principales: | Thakor, Nehal, Holcik, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258125/ https://www.ncbi.nlm.nih.gov/pubmed/21917851 http://dx.doi.org/10.1093/nar/gkr701 |
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