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Regulation of u-PAR gene expression by H2A.Z is modulated by the MEK–ERK/AP-1 pathway
The urokinase receptor (u-PAR) which is largely regulated at the transcriptional level has been implicated in tumor progression. In this study, we explored the epigenetic regulation of u-PAR and showed that the histone variant H2A.Z negatively regulates its expression in multiple cell lines. Chromat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258129/ https://www.ncbi.nlm.nih.gov/pubmed/21937508 http://dx.doi.org/10.1093/nar/gkr725 |