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Direct structural analysis of modified RNA by fluorescent in-line probing

Chemical probing is a common method for the structural characterization of RNA. Typically, RNA is radioactively end-labelled, subjected to probing conditions, and the cleavage fragment pattern is analysed by gel electrophoresis. In recent years, many chemical modifications, like fluorophores, were i...

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Detalles Bibliográficos
Autores principales: Strauss, Benjamin, Nierth, Alexander, Singer, Marco, Jäschke, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258135/
https://www.ncbi.nlm.nih.gov/pubmed/21917852
http://dx.doi.org/10.1093/nar/gkr733