A dual role of BRCA1 in two distinct homologous recombination mediated repair in response to replication arrest

Homologous recombination (HR) is a major mechanism utilized to repair blockage of DNA replication forks. Here, we report that a sister chromatid exchange (SCE) generated by crossover-associated HR efficiently occurs in response to replication fork stalling before any measurable DNA double-strand bre...

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Detalles Bibliográficos
Autores principales: Feng, Zhihui, Zhang, Junran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258139/
https://www.ncbi.nlm.nih.gov/pubmed/21954437
http://dx.doi.org/10.1093/nar/gkr748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258139/
https://www.ncbi.nlm.nih.gov/pubmed/21954437
http://dx.doi.org/10.1093/nar/gkr748

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