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New insights into the fundamental role of topological constraints as a determinant of two-way junction conformation

Recent studies have shown that topological constraints encoded at the RNA secondary structure level involving basic steric and stereochemical forces can significantly restrict the orientations sampled by helices across two-way RNA junctions. Here, we formulate these topological constraints in greate...

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Detalles Bibliográficos
Autores principales: Mustoe, Anthony M., Bailor, Maximillian H., Teixeira, Robert M., Brooks, Charles L., Al-Hashimi, Hashim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258142/
https://www.ncbi.nlm.nih.gov/pubmed/21937512
http://dx.doi.org/10.1093/nar/gkr751