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Modeling the relative relationship of transcription factor binding and histone modifications to gene expression levels in mouse embryonic stem cells

Transcription factor (TF) binding and histone modification (HM) are important for the precise control of gene expression. Hence, we constructed statistical models to relate these to gene expression levels in mouse embryonic stem cells. While both TF binding and HMs are highly ‘predictive’ of gene ex...

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Detalles Bibliográficos
Autores principales: Cheng, Chao, Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258143/
https://www.ncbi.nlm.nih.gov/pubmed/21926158
http://dx.doi.org/10.1093/nar/gkr752