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Retroviral GAG proteins recruit AGO2 on viral RNAs without affecting RNA accumulation and translation

Cellular micro(mi)RNAs are able to recognize viral RNAs through imperfect micro-homologies. Similar to the miRNA-mediated repression of cellular translation, this recognition is thought to tether the RNAi machinery, in particular Argonaute 2 (AGO2) on viral messengers and eventually to modulate viru...

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Detalles Bibliográficos
Autores principales: Bouttier, Manuella, Saumet, Anne, Peter, Marion, Courgnaud, Valérie, Schmidt, Ute, Cazevieille, Chantal, Bertrand, Edouard, Lecellier, Charles-Henri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258151/
https://www.ncbi.nlm.nih.gov/pubmed/21948796
http://dx.doi.org/10.1093/nar/gkr762