REV1 and polymerase ζ facilitate homologous recombination repair

REV1 and DNA Polymerase ζ (REV3 and REV7) play important roles in translesion DNA synthesis (TLS) in which DNA replication bypasses blocking lesions. REV1 and Polζ have also been implicated in promoting repair of DNA double-stranded breaks (DSBs). However, the mechanism by which these two TLS polyme...

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Detalles Bibliográficos
Autores principales: Sharma, Shilpy, Hicks, J. Kevin, Chute, Colleen L., Brennan, Julia R., Ahn, Joon-Young, Glover, Thomas W., Canman, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258153/
https://www.ncbi.nlm.nih.gov/pubmed/21926160
http://dx.doi.org/10.1093/nar/gkr769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258153/
https://www.ncbi.nlm.nih.gov/pubmed/21926160
http://dx.doi.org/10.1093/nar/gkr769

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