Transcriptional activation by mitochondrial transcription factor A involves preferential distortion of promoter DNA

Mitochondrial transcription factor A (mtTFA/TFAM) is a nucleus-encoded, high-mobility-group-box (HMG-box) protein that regulates transcription of the mitochondrial genome by specifically recognizing light-strand and heavy-strand promoters (LSP, HSP1). TFAM also binds mitochondrial DNA in a non-seque...

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Detalles Bibliográficos
Autores principales: Malarkey, Christopher S., Bestwick, Megan, Kuhlwilm, Jane E., Shadel, Gerald S., Churchill, Mair E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258160/
https://www.ncbi.nlm.nih.gov/pubmed/21948790
http://dx.doi.org/10.1093/nar/gkr787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258160/
https://www.ncbi.nlm.nih.gov/pubmed/21948790
http://dx.doi.org/10.1093/nar/gkr787

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