PLCζ causes Ca(2+) oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P(2)

Sperm-specific phospholipase C ζ (PLCζ) activates embryo development by triggering intracellular Ca(2+) oscillations in mammalian eggs indistinguishable from those at fertilization. Somatic PLC isozymes generate inositol 1,4,5-trisphophate–mediated Ca(2+) release by hydrolyzing phosphatidylinositol...

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Detalles Bibliográficos
Autores principales: Yu, Yuansong, Nomikos, Michail, Theodoridou, Maria, Nounesis, George, Lai, F. Anthony, Swann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258180/
https://www.ncbi.nlm.nih.gov/pubmed/22114355
http://dx.doi.org/10.1091/mbc.E11-08-0687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258180/
https://www.ncbi.nlm.nih.gov/pubmed/22114355
http://dx.doi.org/10.1091/mbc.E11-08-0687

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