A mass spectrometry-guided genome mining approach for natural product peptidogenomics

Peptide natural products exhibit broad biological properties and are commonly produced by orthogonal ribosomal and nonribosomal pathways in prokaryotes and eukaryotes. To harvest this large and diverse resource of bioactive molecules, we introduce Natural Product Peptidogenomics (NPP), a new mass sp...

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Detalles Bibliográficos
Autores principales: Kersten, Roland D., Yang, Yu-Liang, Xu, Yuquan, Cimermancic, Peter, Nam, Sang-Jip, Fenical, William, Fischbach, Michael A., Moore, Bradley S., Dorrestein, Pieter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258187/
https://www.ncbi.nlm.nih.gov/pubmed/21983601
http://dx.doi.org/10.1038/nchembio.684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258187/
https://www.ncbi.nlm.nih.gov/pubmed/21983601
http://dx.doi.org/10.1038/nchembio.684

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