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A mass spectrometry-guided genome mining approach for natural product peptidogenomics
Peptide natural products exhibit broad biological properties and are commonly produced by orthogonal ribosomal and nonribosomal pathways in prokaryotes and eukaryotes. To harvest this large and diverse resource of bioactive molecules, we introduce Natural Product Peptidogenomics (NPP), a new mass sp...
Autores principales: | Kersten, Roland D., Yang, Yu-Liang, Xu, Yuquan, Cimermancic, Peter, Nam, Sang-Jip, Fenical, William, Fischbach, Michael A., Moore, Bradley S., Dorrestein, Pieter C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258187/ https://www.ncbi.nlm.nih.gov/pubmed/21983601 http://dx.doi.org/10.1038/nchembio.684 |
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