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CXCR4/CXCL12 Participate in Extravasation of Metastasizing Breast Cancer Cells within the Liver in a Rat Model

INTRODUCTION: Organ-specific composition of extracellular matrix proteins (ECM) is a determinant of metastatic host organ involvement. The chemokine CXCL12 and its receptor CXCR4 play important roles in the colonization of human breast cancer cells to their metastatic target organs. In this study, w...

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Detalles Bibliográficos
Autores principales: Wendel, Claudia, Hemping-Bovenkerk, André, Krasnyanska, Julia, Mees, Sören Torge, Kochetkova, Marina, Stoeppeler, Sandra, Haier, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258260/
https://www.ncbi.nlm.nih.gov/pubmed/22253872
http://dx.doi.org/10.1371/journal.pone.0030046