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Identification of proprotein convertase substrates using genome-wide expression correlation analysis

BACKGROUND: Subtilisin/kexin-like proprotein convertase (PCSK) enzymes have important regulatory function in a wide variety of biological processes. PCSKs proteolytically process at a target sequence that contains basic amino acids arginine and lysine, which results in functional maturation of the t...

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Detalles Bibliográficos
Autores principales: Turpeinen, Hannu, Kukkurainen, Sampo, Pulkkinen, Kati, Kauppila, Timo, Ojala, Kalle, Hytönen, Vesa P, Pesu, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258279/
https://www.ncbi.nlm.nih.gov/pubmed/22185580
http://dx.doi.org/10.1186/1471-2164-12-618