Identification of a mtDNA mutation hotspot in UV-induced mouse skin tumors producing altered cellular biochemistry

There is increasing awareness of a role of mtDNA alterations in the development of cancer since mtDNA point mutations are found at high frequency in a variety of human tumors. To determine the biological effects of mtDNA mutations in UV-induced skin tumors, hairless mice were irradiated to produce t...

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Detalles Bibliográficos
Autores principales: Jandova, Jana, Eshaghian, Alex, Shi, Mingjian, Li, Meiling, King, Lloyd E, Janda, Jaroslav, Sligh, James E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258376/
https://www.ncbi.nlm.nih.gov/pubmed/22011905
http://dx.doi.org/10.1038/jid.2011.320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258376/
https://www.ncbi.nlm.nih.gov/pubmed/22011905
http://dx.doi.org/10.1038/jid.2011.320

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