Effects of a novel DNA methyltransferase inhibitor Zebularine on human lens epithelial cells

PURPOSE: Posterior capsular opacification (PCO) is a common long-term complication of modern cataract surgery. We have shown that Zebularine, an inhibitor of DNA methylation, suppresses transforming growth factor-β (TGFβ)-induced lens epithelial cells (LECs)–myofibroblasts transdifferentiation. The...

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Detalles Bibliográficos
Autores principales: Zhou, Peng, Lu, Yi, Sun, Xing-Huai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258523/
https://www.ncbi.nlm.nih.gov/pubmed/22259221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258523/
https://www.ncbi.nlm.nih.gov/pubmed/22259221

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