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Inhaled Nitric Oxide Therapy Fails to Improve Outcome in Experimental Severe Influenza

In vitro, nitric oxide (NO) has been shown to have antimicrobial activity against a wide range of viruses, including influenza A virus. Therefore, we hypothesized that inhaled nitric oxide (iNO) would increase survival in vivo by reducing the viral load in C57Bl/6 mice infected with a lethal dose of...

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Detalles Bibliográficos
Autores principales: Darwish, Ilyse, Miller, Chris, Kain, Kevin C., Liles, W. Conrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258558/
https://www.ncbi.nlm.nih.gov/pubmed/22253563
http://dx.doi.org/10.7150/ijms.3880