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Simvastatin Modulates Remodeling of Kv4.3 Expression in Rat Hypertrophied Cardiomyocytes

Objectives: Hypertrophy has been shown to be associated with arrhythmias which can be caused by abnormal remodeling of the Kv4-family of transient potassium channels. Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) have recently been shown to exert pleiotropic protective effe...

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Detalles Bibliográficos
Autores principales: Su, Feifei, Shi, Miaoqian, Yan, Zhiqiang, Ou, Dongbo, Li, Juntang, Lu, Zifan, Zheng, Qiangsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258563/
https://www.ncbi.nlm.nih.gov/pubmed/22253567