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Association of common variants in JAK2 gene with reduced risk of metabolic syndrome and related disorders

BACKGROUND: Disturbances in leptin and insulin signaling pathways are related to obesity and metabolic syndrome (MS) with increased risk of diabetes and cardiovascular disease. Janus kinase 2 (JAK2) is a tyrosine kinase involved in the activation of mechanisms that mediate leptin and insulin actions...

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Detalles Bibliográficos
Autores principales: Penas-Steinhardt, Alberto, Tellechea¹, Mariana L, Gomez-Rosso, Leonardo, Brites, Fernando, Frechtel, Gustavo D, Poskus, Edgardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259043/
https://www.ncbi.nlm.nih.gov/pubmed/22185674
http://dx.doi.org/10.1186/1471-2350-12-166