Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats

BACKGROUND: Members of the mammalian nucleotide binding domain, leucine-rich repeat (LRR)-containing receptor (NLR) family of proteins are key modulators of innate immunity regulating inflammation. Our previous work has shown that among the members of this family, NLRP1/NALP1, present in neurons, pl...

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Detalles Bibliográficos
Autores principales: Mawhinney, Lana J, de Rivero Vaccari, Juan Pablo, Dale, Gordon A, Keane, Robert W, Bramlett, Helen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259063/
https://www.ncbi.nlm.nih.gov/pubmed/22133203
http://dx.doi.org/10.1186/1471-2202-12-123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259063/
https://www.ncbi.nlm.nih.gov/pubmed/22133203
http://dx.doi.org/10.1186/1471-2202-12-123

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