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Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines
BACKGROUND: Cancer cells harbor a large number of molecular alterations such as mutations, amplifications and deletions on DNA sequences and epigenetic changes on DNA methylations. These aberrations may dysregulate gene expressions, which in turn drive the malignancy of tumors. Deciphering the causa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259106/ https://www.ncbi.nlm.nih.gov/pubmed/22051105 http://dx.doi.org/10.1186/1752-0509-5-186 |