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Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines

BACKGROUND: Cancer cells harbor a large number of molecular alterations such as mutations, amplifications and deletions on DNA sequences and epigenetic changes on DNA methylations. These aberrations may dysregulate gene expressions, which in turn drive the malignancy of tumors. Deciphering the causa...

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Detalles Bibliográficos
Autores principales: Li, Shyh-Dar, Tagami, Tatsuaki, Ho, Ying-Fu, Yeang, Chen-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259106/
https://www.ncbi.nlm.nih.gov/pubmed/22051105
http://dx.doi.org/10.1186/1752-0509-5-186