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Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway

BACKGROUND: Microglia are the principal cells involved in the innate immune response in the CNS. Activated microglia produce a number of proinflammatory cytokines implicated in neurotoxicity but they also are a major source of anti-inflammatory cytokines, antiviral proteins and growth factors. There...

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Detalles Bibliográficos
Autores principales: Tarassishin, Leonid, Suh, Hyeon-Sook, Lee, Sunhee C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259120/
https://www.ncbi.nlm.nih.gov/pubmed/22208359
http://dx.doi.org/10.1186/1742-2094-8-187