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Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway
BACKGROUND: Microglia are the principal cells involved in the innate immune response in the CNS. Activated microglia produce a number of proinflammatory cytokines implicated in neurotoxicity but they also are a major source of anti-inflammatory cytokines, antiviral proteins and growth factors. There...
Autores principales: | Tarassishin, Leonid, Suh, Hyeon-Sook, Lee, Sunhee C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259120/ https://www.ncbi.nlm.nih.gov/pubmed/22208359 http://dx.doi.org/10.1186/1742-2094-8-187 |
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