Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assay

Noroviruses are the major cause of food- or water-borne gastroenteritis outbreaks in humans. The norovirus protease that cleaves a large viral polyprotein to nonstructural proteins is essential for virus replication and an attractive target for antiviral drug development. Noroviruses show high genet...

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Detalles Bibliográficos
Autores principales: Chang, Kyeong-Ok, Takahashi, Daisuke, Prakash, Om, Kim, Yunjeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259199/
https://www.ncbi.nlm.nih.gov/pubmed/22200497
http://dx.doi.org/10.1016/j.virol.2011.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259199/
https://www.ncbi.nlm.nih.gov/pubmed/22200497
http://dx.doi.org/10.1016/j.virol.2011.12.002

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