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Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assay
Noroviruses are the major cause of food- or water-borne gastroenteritis outbreaks in humans. The norovirus protease that cleaves a large viral polyprotein to nonstructural proteins is essential for virus replication and an attractive target for antiviral drug development. Noroviruses show high genet...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259199/ https://www.ncbi.nlm.nih.gov/pubmed/22200497 http://dx.doi.org/10.1016/j.virol.2011.12.002 |