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Differential effects of CXCR4 antagonists on the survival and proliferation of myeloid leukemia cells in vitro

BACKGROUND: Antagonists of CXC chemokine receptor 4 (CXCR4), including AMD3100, induce peripheral mobilization of hematopoietic stem cells and have been approved for clinical use. We explored whether the CXCR4 antagonists affected the survival and proliferation of myeloid leukemia cells in vitro. ME...

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Detalles Bibliográficos
Autores principales: Kim, Ha-Yon, Hwang, Ji-Young, Oh, Yoon-Suk, Kim, Seong-Woo, Lee, Hyo-Jin, Yun, Hwan-Jung, Kim, Samyong, Yang, Young-Jun, Jo, Deog-Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259516/
https://www.ncbi.nlm.nih.gov/pubmed/22259630
http://dx.doi.org/10.5045/kjh.2011.46.4.244