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Mouse Models of Aneuploidy

Abnormalities of chromosome copy number are called aneuploidies and make up a large health load on the human population. Many aneuploidies are lethal because the resulting abnormal gene dosage is highly deleterious. Nevertheless, some whole chromosome aneuploidies can lead to live births. Alteration...

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Detalles Bibliográficos
Autores principales: Sheppard, Olivia, Wiseman, Frances K., Ruparelia, Aarti, Tybulewicz, Victor L. J., Fisher, Elizabeth M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259538/
https://www.ncbi.nlm.nih.gov/pubmed/22262951
http://dx.doi.org/10.1100/2012/214078