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Transcriptional characteristics of CD4(+) T cells in young asthmatic children: RORC and FOXP3 axis

BACKGROUND: Asthma is a chronic inflammatory disorder, hypothetically caused by autoreactive Th2 cells, whereas Th1 and regulatory T cells may confer protection. The development of Th subpopulations is dependent on the expression of lineage-specific transcription factors. PURPOSE: This study aimed t...

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Detalles Bibliográficos
Autores principales: Hamzaoui, Agnes, Maalmi, Haïfa, Berraïes, Anissa, Abid, Hanadi, Ammar, Jamel, Hamzaoui, Kamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259694/
https://www.ncbi.nlm.nih.gov/pubmed/22259252
http://dx.doi.org/10.2147/JIR.S25314