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Transcriptional characteristics of CD4(+) T cells in young asthmatic children: RORC and FOXP3 axis
BACKGROUND: Asthma is a chronic inflammatory disorder, hypothetically caused by autoreactive Th2 cells, whereas Th1 and regulatory T cells may confer protection. The development of Th subpopulations is dependent on the expression of lineage-specific transcription factors. PURPOSE: This study aimed t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259694/ https://www.ncbi.nlm.nih.gov/pubmed/22259252 http://dx.doi.org/10.2147/JIR.S25314 |