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Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells

AXL is a receptor tyrosine kinase of the TAM family, the function of which is poorly understood. We previously identified AXL overexpression in Imatinib (IM)-resistant CML cell lines and patients. The present study was conducted to investigate the role of AXL and the mechanisms underlying AXL overex...

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Detalles Bibliográficos
Autores principales: Dufies, Maeva, Jacquel, Arnaud, Belhacene, Nathalie, Robert, Guillaume, Cluzeau, Thomas, Luciano, Fréderic, Cassuto, Jill Patrice, Raynaud, Sophie, Auberger, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259992/
https://www.ncbi.nlm.nih.gov/pubmed/22141136