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Broad inhibition of plasmodium falciparum cytoadherence by (+)-epigallocatechin gallate
BACKGROUND: The surface antigen PfEMP-1 is a key virulence factor of the human malaria parasite implicated in the cytoadherence of Plasmodium falciparum infected erythrocytes to a range of receptors on host endothelium. Among these host receptors, binding to ICAM-1 is related to cerebral malaria. Th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260111/ https://www.ncbi.nlm.nih.gov/pubmed/22132804 http://dx.doi.org/10.1186/1475-2875-10-348 |