Oral bioavailability of the ether lipid plasmalogen precursor, PPI-1011, in the rabbit: a new therapeutic strategy for Alzheimer's disease

INTRODUCTION: Docosahexaenoic acid (DHA) and DHA-containing ethanolamine plasmalogens (PlsEtn) are decreased in the brain, liver and the circulation in Alzheimer's disease. Decreased supply of plasmalogen precursors to the brain by the liver, as a result of peroxisomal deficits is a process tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Wood, Paul L, Smith, Tara, Lane, Nina, Khan, M Amin, Ehrmantraut, Greg, Goodenowe, Dayan B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260122/
https://www.ncbi.nlm.nih.gov/pubmed/22142382
http://dx.doi.org/10.1186/1476-511X-10-227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260122/
https://www.ncbi.nlm.nih.gov/pubmed/22142382
http://dx.doi.org/10.1186/1476-511X-10-227

Ejemplares similares