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Oral bioavailability of the ether lipid plasmalogen precursor, PPI-1011, in the rabbit: a new therapeutic strategy for Alzheimer's disease

INTRODUCTION: Docosahexaenoic acid (DHA) and DHA-containing ethanolamine plasmalogens (PlsEtn) are decreased in the brain, liver and the circulation in Alzheimer's disease. Decreased supply of plasmalogen precursors to the brain by the liver, as a result of peroxisomal deficits is a process tha...

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Detalles Bibliográficos
Autores principales:	Wood, Paul L, Smith, Tara, Lane, Nina, Khan, M Amin, Ehrmantraut, Greg, Goodenowe, Dayan B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260122/ https://www.ncbi.nlm.nih.gov/pubmed/22142382 http://dx.doi.org/10.1186/1476-511X-10-227

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