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Angiopoietin 2 Alters Pancreatic Vascularization in Diabetic Conditions

AIMS/HYPOTHESIS: Islet vascularization, by controlling beta-cell mass expansion in response to increased insulin demand, is implicated in the progression to glucose intolerance and type 2 diabetes. We investigated how hyperglycaemia impairs expansion and differentiation of the growing pancreas. We h...

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Detalles Bibliográficos
Autores principales: Calderari, Sophie, Chougnet, Cécile, Clemessy, Maud, Kempf, Hervé, Corvol, Pierre, Larger, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260141/
https://www.ncbi.nlm.nih.gov/pubmed/22272235
http://dx.doi.org/10.1371/journal.pone.0029438