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Angiopoietin 2 Alters Pancreatic Vascularization in Diabetic Conditions
AIMS/HYPOTHESIS: Islet vascularization, by controlling beta-cell mass expansion in response to increased insulin demand, is implicated in the progression to glucose intolerance and type 2 diabetes. We investigated how hyperglycaemia impairs expansion and differentiation of the growing pancreas. We h...
Autores principales: | Calderari, Sophie, Chougnet, Cécile, Clemessy, Maud, Kempf, Hervé, Corvol, Pierre, Larger, Etienne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260141/ https://www.ncbi.nlm.nih.gov/pubmed/22272235 http://dx.doi.org/10.1371/journal.pone.0029438 |
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