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Tyrosine Nitration of PA700 Links Proteasome Activation to Endothelial Dysfunction in Mouse Models with Cardiovascular Risk Factors

Oxidative stress is believed to cause endothelial dysfunction, an early event and a hallmark in cardiovascular diseases (CVD) including hypertension, diabetes, and dyslipidemia. However, the targets for oxidative stress-mediated endothelial dysfunction in CVD have not been completely elucidated. Her...

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Detalles Bibliográficos
Autores principales: Xu, Jian, Wang, Shuangxi, Zhang, Miao, Wang, Qilong, Asfa, Sima, Zou, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260160/
https://www.ncbi.nlm.nih.gov/pubmed/22272240
http://dx.doi.org/10.1371/journal.pone.0029649