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Anti-IL-2 Treatment Impairs the Expansion of T(reg) Cell Population during Acute Malaria and Enhances the Th1 Cell Response at the Chronic Disease

Plasmodium chabaudi infection induces a rapid and intense splenic CD4(+) T cell response that contributes to both disease pathogenesis and the control of acute parasitemia. The subsequent development of clinical immunity to disease occurs concomitantly with the persistence of low levels of chronic p...

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Detalles Bibliográficos
Autores principales: Zago, Cláudia A., Bortoluci, Karina R., Sardinha, Luiz R., Pretel, Fernando D., Castillo-Méndez, Sheyla I., Freitas do Rosário, Ana Paula, Hiyane, Meire I., Muxel, Sandra M., Rodriguez-Málaga, Sérgio M., Abrahamsohn, Ises A., Álvarez, José M., D'Império Lima, Maria Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260167/
https://www.ncbi.nlm.nih.gov/pubmed/22272258
http://dx.doi.org/10.1371/journal.pone.0029894