HERC6 Is the Main E3 Ligase for Global ISG15 Conjugation in Mouse Cells

Type I interferon (IFN) stimulates expression and conjugation of the ubiquitin-like modifier IFN-stimulated gene 15 (ISG15), thereby restricting replication of a wide variety of viruses. Conjugation of ISG15 is critical for its antiviral activity in mice. HECT domain and RCC1-like domain containing...

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Detalles Bibliográficos
Autores principales: Oudshoorn, Diede, van Boheemen, Sander, Sánchez-Aparicio, Maria Teresa, Rajsbaum, Ricardo, García-Sastre, Adolfo, Versteeg, Gijs A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260183/
https://www.ncbi.nlm.nih.gov/pubmed/22272257
http://dx.doi.org/10.1371/journal.pone.0029870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260183/
https://www.ncbi.nlm.nih.gov/pubmed/22272257
http://dx.doi.org/10.1371/journal.pone.0029870

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