Evolution of the Primate APOBEC3A Cytidine Deaminase Gene and Identification of Related Coding Regions

The APOBEC3 gene cluster encodes six cytidine deaminases (A3A-C, A3DE, A3F-H) with single stranded DNA (ssDNA) substrate specificity. For the moment A3A is the only enzyme that can initiate catabolism of both mitochondrial and nuclear DNA. Human A3A expression is initiated from two different methion...

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Detalles Bibliográficos
Autores principales: Henry, Michel, Terzian, Christophe, Peeters, Martine, Wain-Hobson, Simon, Vartanian, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260193/
https://www.ncbi.nlm.nih.gov/pubmed/22272271
http://dx.doi.org/10.1371/journal.pone.0030036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260193/
https://www.ncbi.nlm.nih.gov/pubmed/22272271
http://dx.doi.org/10.1371/journal.pone.0030036

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