Fluoxetine Counteracts the Cognitive and Cellular Effects of 5-Fluorouracil in the Rat Hippocampus by a Mechanism of Prevention Rather than Recovery

5-Fluorouracil (5-FU) is a cytostatic drug associated with chemotherapy-induced cognitive impairments that many cancer patients experience after treatment. Previous work in rodents has shown that 5-FU reduces hippocampal cell proliferation, a possible mechanism for the observed cognitive impairment,...

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Detalles Bibliográficos
Autores principales: Lyons, Laura, ELBeltagy, Maha, Bennett, Geoffrey, Wigmore, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260195/
https://www.ncbi.nlm.nih.gov/pubmed/22272269
http://dx.doi.org/10.1371/journal.pone.0030010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260195/
https://www.ncbi.nlm.nih.gov/pubmed/22272269
http://dx.doi.org/10.1371/journal.pone.0030010

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