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Fluoxetine Counteracts the Cognitive and Cellular Effects of 5-Fluorouracil in the Rat Hippocampus by a Mechanism of Prevention Rather than Recovery
5-Fluorouracil (5-FU) is a cytostatic drug associated with chemotherapy-induced cognitive impairments that many cancer patients experience after treatment. Previous work in rodents has shown that 5-FU reduces hippocampal cell proliferation, a possible mechanism for the observed cognitive impairment,...
| Autores principales: | , , , |
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| 格式: | Online Artículo Texto |
| 語言: | English |
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Public Library of Science
2012
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| 主題: | |
| 在線閱讀: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260195/ https://www.ncbi.nlm.nih.gov/pubmed/22272269 http://dx.doi.org/10.1371/journal.pone.0030010 |