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Disturbance of the OPG/RANK/RANKL pathway and systemic inflammation in COPD patients with emphysema and osteoporosis

BACKGROUND: Osteoporosis is one of the systemic features of COPD. A correlation between the emphysema phenotype of COPD and reduced bone mineral density (BMD) is suggested by some studies, however, the mechanisms underlying this relationship are unclear. Experimental studies indicate that IL-1β, IL-...

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Detalles Bibliográficos
Autores principales: Bai, Peng, Sun, Yongchang, Jin, Jianmin, Hou, Jia, Li, Ran, Zhang, Qing, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260206/
https://www.ncbi.nlm.nih.gov/pubmed/22176920
http://dx.doi.org/10.1186/1465-9921-12-157