Erythrocyte Inosine Triphosphatase Activity Is Decreased in HIV-Seropositive Individuals

BACKGROUND: Inosine triphosphatase (ITPase) is encoded by the polymorphic gene ITPA and maintains low intracellular levels of the inosine nucleotides ITP and dITP. The most frequently reported polymorphisms are ITPA c.94C>A (rs 1127354) and ITPA c. 124+21 A>C (rs7270101). Some nucleoside-analo...

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Detalles Bibliográficos
Autores principales: Bierau, Jörgen, Bakker, Jaap A., Schippers, Jolanda A., Grashorn, Janine A. C., Lindhout, Martijn, Lowe, Selwyn H., Paulussen, Aimée D. C., Verbon, Annelies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260219/
https://www.ncbi.nlm.nih.gov/pubmed/22272297
http://dx.doi.org/10.1371/journal.pone.0030175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260219/
https://www.ncbi.nlm.nih.gov/pubmed/22272297
http://dx.doi.org/10.1371/journal.pone.0030175

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