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A MusD Retrotransposon Insertion in the Mouse Slc6a5 Gene Causes Alterations in Neuromuscular Junction Maturation and Behavioral Phenotypes

Glycine is the major inhibitory neurotransmitter in the spinal cord and some brain regions. The presynaptic glycine transporter, GlyT2, is required for sustained glycinergic transmission through presynaptic reuptake and recycling of glycine. Mutations in SLC6A5, encoding GlyT2, cause hereditary hype...

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Detalles Bibliográficos
Autores principales: Bogdanik, Laurent P., Chapman, Harold D., Miers, Kathy E., Serreze, David V., Burgess, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260239/
https://www.ncbi.nlm.nih.gov/pubmed/22272310
http://dx.doi.org/10.1371/journal.pone.0030217