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Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblasts
BACKGROUND: Lung fibrosis is characterized by fibroblast proliferation and the deposition of collagens. Curcumin, a polyphenol antioxidant from the spice tumeric, has been shown to effectively counteract fibroblast proliferation and reducing inflammation and fibrotic progression in animal models of...
Autores principales: | Zhang, Dongwei, Huang, Chuangfang, Yang, Changfu, Liu, Renzuo J, Wang, Jifeng, Niu, Jianzhao, Brömme, Dieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260240/ https://www.ncbi.nlm.nih.gov/pubmed/22126332 http://dx.doi.org/10.1186/1465-9921-12-154 |
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