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Wogonin Improves Histological and Functional Outcomes, and Reduces Activation of TLR4/NF-κB Signaling after Experimental Traumatic Brain Injury

BACKGROUND: Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that contributes to neuronal damage and behavioral impairment. This study was undertaken to investigate the effects of wogonin, a flavonoid with potent anti-inflammatory properties, on functional and histological outcomes...

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Detalles Bibliográficos
Autores principales: Chen, Chien-Cheng, Hung, Tai-Ho, Wang, Yen-Ho, Lin, Chii-Wann, Wang, Pei-Yi, Lee, Chun-Yen, Chen, Szu-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260265/
https://www.ncbi.nlm.nih.gov/pubmed/22272328
http://dx.doi.org/10.1371/journal.pone.0030294