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Wogonin Improves Histological and Functional Outcomes, and Reduces Activation of TLR4/NF-κB Signaling after Experimental Traumatic Brain Injury
BACKGROUND: Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that contributes to neuronal damage and behavioral impairment. This study was undertaken to investigate the effects of wogonin, a flavonoid with potent anti-inflammatory properties, on functional and histological outcomes...
Autores principales: | Chen, Chien-Cheng, Hung, Tai-Ho, Wang, Yen-Ho, Lin, Chii-Wann, Wang, Pei-Yi, Lee, Chun-Yen, Chen, Szu-Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260265/ https://www.ncbi.nlm.nih.gov/pubmed/22272328 http://dx.doi.org/10.1371/journal.pone.0030294 |
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