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Accounting For Alignment Uncertainty in Phylogenomics

Uncertainty in multiple sequence alignments has a large impact on phylogenetic analyses. Little has been done to evaluate the quality of individual positions in protein sequence alignments, which directly impact the accuracy of phylogenetic trees. Here we describe ZORRO, a probabilistic masking prog...

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Detalles Bibliográficos
Autores principales: Wu, Martin, Chatterji, Sourav, Eisen, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260272/
https://www.ncbi.nlm.nih.gov/pubmed/22272325
http://dx.doi.org/10.1371/journal.pone.0030288