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Accounting For Alignment Uncertainty in Phylogenomics
Uncertainty in multiple sequence alignments has a large impact on phylogenetic analyses. Little has been done to evaluate the quality of individual positions in protein sequence alignments, which directly impact the accuracy of phylogenetic trees. Here we describe ZORRO, a probabilistic masking prog...
Autores principales: | Wu, Martin, Chatterji, Sourav, Eisen, Jonathan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260272/ https://www.ncbi.nlm.nih.gov/pubmed/22272325 http://dx.doi.org/10.1371/journal.pone.0030288 |
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