CD49f and CD61 identify Her2/neu-induced mammary tumor initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling

HER2/Neu is overexpressed in 20-30% of breast cancers and associated with aggressive phenotypes and poor prognosis. For deciphering the role of HER2/Neu in breast cancer, mouse mammary tumor virus (MMTV)-Her2/neu transgenic mice that develop mammary tumors resembling human HER2-subtype breast cancer...

Descripción completa

Detalles Bibliográficos
Autores principales: Lo, Pang-Kuo, Kanojia, Deepak, Liu, Xinfeng, Singh, Udai P., Berger, Franklin G., Wang, Qian, Chen, Hexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260386/
https://www.ncbi.nlm.nih.gov/pubmed/21996747
http://dx.doi.org/10.1038/onc.2011.439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260386/
https://www.ncbi.nlm.nih.gov/pubmed/21996747
http://dx.doi.org/10.1038/onc.2011.439

Ejemplares similares