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DNA glycosylases: in DNA repair and beyond

The base excision repair machinery protects DNA in cells from the damaging effects of oxidation, alkylation, and deamination; it is specialized to fix single-base damage in the form of small chemical modifications. Base modifications can be mutagenic and/or cytotoxic, depending on how they interfere...

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Detalles Bibliográficos
Autores principales: Jacobs, Angelika L., Schär, Primo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260424/
https://www.ncbi.nlm.nih.gov/pubmed/22048164
http://dx.doi.org/10.1007/s00412-011-0347-4